AZD1080

Catalog No.: A12819
GSK3 inhibitor
AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
Grouped product items
Product Name Price Stock Qty
AZD1080 5mg
$81.00
In stock
AZD1080 10mg
$138.00
In stock
AZD1080 25mg
$243.00
In stock
AZD1080 50mg
$405.00
In stock
AZD1080 10mM * 1mL in DMSO
$206.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AZD1080 has been cited by 1 publications
  • Shengzhong Liu, .et al. , J Cell Biochem, 2019, 2019 PMID: 30887575
  • Biological Activity
    Discription AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
    Targets
    Target Value
    Product Information
    Catalog Num A12819
    Formula C19H18N4O2
    Molecular Weight 334.4
    CAS Number 612487-72-6
    SMILES C1COCCN1CC2=CN/C(=C\3/C4=C(C=CC(=C4)C#N)NC3=O)/C=C2
    Synonyms AZD 1080, AZD-1080
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 49 mg/mL (146.54 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 19 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 29.9 mL 149.52 mL 299.04 mL
    0.5 mM 5.98 mL 29.9 mL 59.81 mL
    1 mM 2.99 mL 14.95 mL 29.9 mL
    5 mM 0.6 mL 2.99 mL 5.98 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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