KPT 335

Catalog No.: A16078
SINE inhibitor
KPT 335 is an orally bioavailable Selective Inhibitor of Nuclear Export (SINE).
Grouped product items
Product Name Price Stock Qty
KPT 335 5mg
$120.00
In stock
KPT 335 10mg
$180.00
In stock
KPT 335 50mg
$780.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription KPT 335 is an orally bioavailable Selective Inhibitor of Nuclear Export (SINE).
Targets
Target Value
Product Information
Catalog Num A16078
Formula C18H12F6N6O
Molecular Weight 442.32
CAS Number 1392136-43-4
SMILES O=C(NNC1=NC=CC=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
Synonyms Verdinexor
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 83 mg/mL (187.65 mM)
Water Insoluble
Ethanol Warmed: 10 mg/mL
In vivo 5% DMSO+corn oil 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.61 mL 113.04 mL 226.08 mL
0.5 mM 4.52 mL 22.61 mL 45.22 mL
1 mM 2.26 mL 11.3 mL 22.61 mL
5 mM 0.45 mL 2.26 mL 4.52 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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