Q-VD-OPh hydrate

Catalog No.: A14915
Caspase inhibitor
Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM).
Grouped product items
Product Name Price Stock Qty
Q-VD-OPh hydrate 5mg
$90.00
In stock
Q-VD-OPh hydrate 10mg
$150.00
In stock
Q-VD-OPh hydrate 25mg
$240.00
In stock
Bulk Size
Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Q-VD-OPh hydrate has been cited by 4 publications
  • Anna L Koessinger, .et al. , Cell Death Differ, 2022, Apr 26 PMID: 35473984
  • Florian J Bock, .et al. , Nat Commun, 2021, Nov 12;12(1):6572 PMID: 34772930
  • Davide Pradella, .et al. , Nat Commun, 2021, 12: 4872 PMID: 34381052
  • Haschka MD, .et al. , Cell Death Differ, 2020, Feb 3 PMID: 32015503
  • Biological Activity
    Discription Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM).
    Targets
    Target Value
    Product Information
    Catalog Num A14915
    Formula C26H25F2N3O6
    Molecular Weight 513.49
    CAS Number 1135695-98-5
    SMILES CC(C)C(C(=O)NC(CC(=O)O)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C2=NC3=CC=CC=C3C=C2
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 94 mg/mL (183.06 mM)
    Water Insoluble
    Ethanol 94 mg/mL (183.06 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.47 mL 97.37 mL 194.75 mL
    0.5 mM 3.89 mL 19.47 mL 38.95 mL
    1 mM 1.95 mL 9.74 mL 19.47 mL
    5 mM 0.39 mL 1.95 mL 3.89 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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