SB 334867

Catalog No.: A12786
OX1 receptor antagonist
SB 334867 is a selective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo.
Grouped product items
Product Name Price Stock Qty
SB 334867 5mg
$40.00
In stock
SB 334867 10mg
$75.00
In stock
SB 334867 25mg
$150.00
In stock
SB 334867 50mg
$250.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's SB 334867 has been cited by 1 publications
  • Tony Ngo, .et al. , Nat Chem Biol, 2017, Feb; 13(2): 235-242 PMID: 27992882
  • Biological Activity
    Discription SB 334867 is a selective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo.
    Targets
    Target Value
    Product Information
    Catalog Num A12786
    Formula C17H13N5O2
    Molecular Weight 319.32
    CAS Number 249889-64-3
    SMILES CC1=NC2=C(O1)C=C(C=C2)NC(=O)NC3=C4C(=NC=C3)C=CC=N4
    Synonyms SB334867,SB-334867
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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