TMP 269

Catalog No.: A14128
HDAC inhibitor
TMP 269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
Grouped product items
Product Name Price Stock Qty
TMP 269 5mg
$80.00
In stock
TMP 269 10mg
$150.00
In stock
TMP 269 25mg
$250.00
In stock
TMP 269 10mM * 1mL in DMSO
$110.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription TMP 269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
Targets
Target Value
Product Information
Catalog Num A14128
Formula C25H21F3N4O3S
Molecular Weight 514.52
CAS Number 1314890-29-3
SMILES O=C(c1cccc(c1)c1noc(n1)C(F)(F)F)NCC1(CCOCC1)c1scc(n1)c1ccccc1
Synonyms TMP-269,TMP269
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 89 mg/mL (172.97 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL (3.88 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.44 mL 97.18 mL 194.36 mL
0.5 mM 3.89 mL 19.44 mL 38.87 mL
1 mM 1.94 mL 9.72 mL 19.44 mL
5 mM 0.39 mL 1.94 mL 3.89 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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