AG-490
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | AG 490 is a selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and ErbB2 respectively). Also inhibits JAK2 with no activity to Lck, Lyn, Btk, Syk and Src. | ||
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Catalog Num | A10047 |
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Formula | C17H14N2O3 |
Molecular Weight | 294.3 |
CAS Number | 133550-30-8 |
SMILES | C1=CC=C(C=C1)CNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N |
Synonyms | Tyrphostin AG490 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 54 mg/mL (183.48 mM) | |
Water | Insoluble | ||
Ethanol | 6 mg/mL | ||
In vivo | 5% DMSO+40% PEG300+5% Tween80+50% ddH2O | 5.93 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 33.98 mL | 169.89 mL | 339.79 mL |
0.5 mM | 6.8 mL | 33.98 mL | 67.96 mL |
1 mM | 3.4 mL | 16.99 mL | 33.98 mL |
5 mM | 0.68 mL | 3.4 mL | 6.8 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2