LDN-214117

Catalog No.: A16096
ALK2 inhibitor
LDN-214117 is a selective and potent ALK2 inhibitor. LDN-214117 inhibited ALK2 most, with a biochemical IC50 of 24 nM.
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Product Name Price Stock Qty
LDN-214117 5mg
$60.00
In stock
LDN-214117 10mg
$110.00
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LDN-214117 50mg
$450.00
In stock
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Biological Activity
Discription LDN-214117 is a selective and potent ALK2 inhibitor. LDN-214117 inhibited ALK2 most, with a biochemical IC50 of 24 nM.
Targets
Target Value
Product Information
Catalog Num A16096
Formula C25H29N3O3
Molecular Weight 419.52
CAS Number 1627503-67-6
SMILES COC1=C(OC)C(OC)=CC(C2=C(C)N=CC(C3=CC=C(N4CCNCC4)C=C3)=C2)=C1
Synonyms LDN214117, LDN 214117
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 74 mg/mL (176.39 mM)
Water Insoluble
Ethanol 74 mg/mL (176.39 mM)
In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.84 mL 119.18 mL 238.37 mL
0.5 mM 4.77 mL 23.84 mL 47.67 mL
1 mM 2.38 mL 11.92 mL 23.84 mL
5 mM 0.48 mL 2.38 mL 4.77 mL
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