T0070907
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | T0070907 was identified as a potent and selective PPARgamma antagonist. With an apparent binding affinity (concentration at 50% inhibition of [(3)H]rosiglitazone binding or IC(50)) of 1 nm, T0070907 covalently modifies PPARgamma on cysteine 313 in helix 3 of human PPARgamma2. | ||
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Catalog Num | A11588 |
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Formula | C12H8ClN3O3 |
Molecular Weight | 277.66 |
CAS Number | 313516-66-4 |
SMILES | ClC1=CC=C([N+]([O-])=O)C=C1C(NC2=CC=NC=C2)=O |
Synonyms | T 0070907 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 24 mg/mL (86.43 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+45% PEG 300+ddH2O | 8 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 36.02 mL | 180.08 mL | 360.15 mL |
0.5 mM | 7.2 mL | 36.02 mL | 72.03 mL |
1 mM | 3.6 mL | 18.01 mL | 36.02 mL |
5 mM | 0.72 mL | 3.6 mL | 7.2 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2