Napabucasin

Catalog No.: A13474
STAT inhibitor
Napabucasin is an orally-administered small molecule which can block cancer stem cell (CSC) self-renewal and induces cell death in CSCs as well as non-stem cancer cells.
Grouped product items
Product Name Price Stock Qty
Napabucasin 10mg
$90.00
In stock
Napabucasin 25mg
$180.00
In stock
Napabucasin 50mg
$225.00
In stock
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Biological Activity
Discription Napabucasin is an orally-administered small molecule which can block cancer stem cell (CSC) self-renewal and induces cell death in CSCs as well as non-stem cancer cells.
Targets
Target Value
Product Information
Catalog Num A13474
Formula C14H8O4
Molecular Weight 240.21
CAS Number 83280-65-3
SMILES O=C(C1=C2OC(C(C)=O)=C1)C3=C(C2=O)C=CC=C3
Synonyms BBI 608, BBI608, BBI-608
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 10 mg/mL (41.63 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+40% PEG 300+5% Tween 80+ddH2O 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.63 mL 208.15 mL 416.3 mL
0.5 mM 8.33 mL 41.63 mL 83.26 mL
1 mM 4.16 mL 20.82 mL 41.63 mL
5 mM 0.83 mL 4.16 mL 8.33 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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