Amphotericin B

Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. Amphotericin B induces K+ leakage, which is separate from its lethal action, as was demonstrated in human erythrocytes and is due to the inhibitory effect on the Na+/K+ pump.
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Product Name Price Stock Qty
Amphotericin B 50mg
$30.00
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Amphotericin B 100mg
$45.00
In stock
Amphotericin B 500mg
$81.00
In stock
Amphotericin B 10mM * 1mL in DMSO
$65.00
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Adooq Products cited in reputable paper
Adooq's Amphotericin B has been cited by 1 publications
  • J Chen, .et al. , Biomater Sci, 2020, Jun 21;8(12):3430-3442 PMID: 32406432
  • Biological Activity
    Discription Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. Amphotericin B induces K+ leakage, which is separate from its lethal action, as was demonstrated in human erythrocytes and is due to the inhibitory effect on the Na+/K+ pump.
    Targets
    Target Value
    Product Information
    Catalog Num A10073
    Formula C47H73NO17
    Molecular Weight 924.1
    CAS Number 1397-89-3
    SMILES C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O
    Synonyms Fungilin, Fungizone, AmBisome, Fungisome, Amphocil, Amphotec
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 20 mg/mL (21.64 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 10.82 mL 54.11 mL 108.21 mL
    0.5 mM 2.16 mL 10.82 mL 21.64 mL
    1 mM 1.08 mL 5.41 mL 10.82 mL
    5 mM 0.22 mL 1.08 mL 2.16 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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