Pexidartinib (PLX3397)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity. | ||
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Targets |
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Catalog Num | A15520 |
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Formula | C20H15ClF3N5 |
Molecular Weight | 417.81 |
CAS Number | 1029044-16-3 |
SMILES | FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F |
Synonyms | PLX-3397, PLX 3397 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 71 mg/mL (169.93 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+45% PEG 300+5% Tween 80+ddH2O | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.93 mL | 119.67 mL | 239.34 mL |
0.5 mM | 4.79 mL | 23.93 mL | 47.87 mL |
1 mM | 2.39 mL | 11.97 mL | 23.93 mL |
5 mM | 0.48 mL | 2.39 mL | 4.79 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2