PF-06447475
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC50 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively. | ||
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Targets |
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Catalog Num | A15504 |
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Formula | C17H15N5O |
Molecular Weight | 305.33 |
CAS Number | 1527473-33-1 |
SMILES | C1COCCN1C2=NC=NC3=C2C(=CN3)C4=CC=CC(=C4)C#N |
Synonyms | PF06447475, PF 06447475 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 56 mg/mL (183.4 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 32.75 mL | 163.76 mL | 327.51 mL |
0.5 mM | 6.55 mL | 32.75 mL | 65.5 mL |
1 mM | 3.28 mL | 16.38 mL | 32.75 mL |
5 mM | 0.66 mL | 3.28 mL | 6.55 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2