PF-00562271

Catalog No.: A12580
FAK inhibitor
PF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively.
Grouped product items
Product Name Price Stock Qty
PF-00562271 5mg
$70.00
In stock
PF-00562271 10mg
$90.00
In stock
PF-00562271 25mg
$180.00
In stock
PF-00562271 50mg
$250.00
In stock
PF-00562271 10mM * 1mL in DMSO
$103.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's PF-00562271 has been cited by 1 publications
  • Dai Sonoda, .et al. , Oncol Rep, 2022, Jan;47(1):19 PMID: 34796907
  • Biological Activity
    Discription PF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A12580
    Formula C21H20F3N7O3S.C6H6O3S
    Molecular Weight 665.66
    CAS Number 939791-38-5
    SMILES CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C.C1=CC=C(C=C1)S(=O)(=O)O
    Synonyms PF00562271, PF 00562271
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 14 mg/mL (21.03 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 4% DMSO+30% PEG 300+ddH2O 2 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 15.02 mL 75.11 mL 150.23 mL
    0.5 mM 3 mL 15.02 mL 30.05 mL
    1 mM 1.5 mL 7.51 mL 15.02 mL
    5 mM 0.3 mL 1.5 mL 3 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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