Selonsertib

Catalog No.: A15991
ASK1 inhibitor
Selonsertib is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.
Grouped product items
Product Name Price Stock Qty
Selonsertib 5mg
$60.00
In stock
Selonsertib 10mg
$110.00
In stock
Selonsertib 50mg
$320.00
In stock
Bulk Size
Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Selonsertib has been cited by 2 publications
  • Lisa M Kim, .et al. , Cancer Res, 2022, Sep 2;82(17):3045-3057 PMID: 35792658
  • Luwa Yuan, .et al. , Sci Rep, 2019, 9:11156 PMID: 31371790
  • Biological Activity
    Discription Selonsertib is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.
    Targets
    Target Value
    Product Information
    Catalog Num A15991
    Formula C24H24FN7O
    Molecular Weight 445.5
    CAS Number 1448428-04-3
    SMILES O=C(NC1=NC(C2=NN=CN2C(C)C)=CC=C1)C3=CC(N4C=C(C5CC5)N=C4)=C(C)C=C3F
    Synonyms GS-4997, GS4997, GS 4997
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 34 mg/mL (76.31 mM)
    Water Insoluble
    Ethanol 23 mg/mL (51.63 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.45 mL 112.23 mL 224.47 mL
    0.5 mM 4.49 mL 22.45 mL 44.89 mL
    1 mM 2.24 mL 11.22 mL 22.45 mL
    5 mM 0.45 mL 2.24 mL 4.49 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

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