Tolnaftate

Catalog No.: A11657
Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. It is believed to inhibit the squalene epoxidase, an important enzyme in the biosynthetic pathway of ergosterol (a key component of the fungal membrane) in a similar way to allylamines.
Grouped product items
Product Name Price Stock Qty
Tolnaftate 1g
$50.00
In stock
Tolnaftate 10mM * 1mL in DMSO
$59.00
In stock
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Biological Activity
Discription Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. It is believed to inhibit the squalene epoxidase, an important enzyme in the biosynthetic pathway of ergosterol (a key component of the fungal membrane) in a similar way to allylamines.
Product Information
Catalog Num A11657
Formula C19H17NOS
Molecular Weight 307.41
CAS Number 2398-96-1
SMILES CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 56 mg/mL (182.16 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.53 mL 162.65 mL 325.3 mL
0.5 mM 6.51 mL 32.53 mL 65.06 mL
1 mM 3.25 mL 16.26 mL 32.53 mL
5 mM 0.65 mL 3.25 mL 6.51 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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