BMH-21

Catalog No.: A14335
RNA polymerase inhibitor
BMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription.
Grouped product items
Product Name Price Stock Qty
BMH-21 5mg
$40.00
In stock
BMH-21 10mg
$65.00
In stock
BMH-21 25mg
$120.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's BMH-21 has been cited by 1 publications
  • Masahiko Okuda, .et al. , Nucleic Acids Res, 2021, Jul 16 PMID: 34268577
  • Biological Activity
    Discription BMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription.
    Targets
    Target Value
    Product Information
    Catalog Num A14335
    Formula C21H20N4O2
    Molecular Weight 360.4
    CAS Number 896705-16-1
    SMILES CN(C)CCNC(=O)C1=CC=CN2C1=NC3=CC4=CC=CC=C4C=C3C2=O
    Synonyms BMH21, BMH 21
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO Warmed: 4 mg/mL (11.1 mM)
    Water Insoluble
    Ethanol Warmed: 2 mg/mL (5.54 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.75 mL 138.73 mL 277.47 mL
    0.5 mM 5.55 mL 27.75 mL 55.49 mL
    1 mM 2.77 mL 13.87 mL 27.75 mL
    5 mM 0.55 mL 2.77 mL 5.55 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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