EW-7197 (Vactosertib)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | EW-7197 is a highly potent, selective, and orally bioavailable TGF-β I receptor ALK4/ALK5 inhibitor with IC50 of 13 nM and 11 nM, respectively | ||
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Targets |
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Catalog Num | A14213 |
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Formula | C22H18FN7 |
Molecular Weight | 399.42 |
CAS Number | 1352608-82-2 |
SMILES | CC1=CC=CC(=N1)C2=C(N=C(N2)CNC3=CC=CC=C3F)C4=CN5C(=NC=N5)C=C4 |
Synonyms | EW7197 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 77 mg/mL (192.77 mM) | |
Water | Insoluble | ||
Ethanol | 42 mg/mL (105.15 mM) | ||
In vivo | 1%cmc-na | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.04 mL | 125.18 mL | 250.36 mL |
0.5 mM | 5.01 mL | 25.04 mL | 50.07 mL |
1 mM | 2.5 mL | 12.52 mL | 25.04 mL |
5 mM | 0.5 mL | 2.5 mL | 5.01 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2