FLI-06

Catalog No.: A13815
Gamma-secretase inhibitor
FLI-06 is a Notch inhibitor and the early secretory pathway inhibitor. FLI-06 disrupts the Golgi apparatus in a manner distinct from that of brefeldin A and golgicide A.
Grouped product items
Product Name Price Stock Qty
FLI-06 10mg
$120.00
In stock
FLI-06 25mg
$225.00
In stock
FLI-06 50mg
$400.00
In stock
FLI-06 100mg
$700.00
In stock
FLI-06 10mM * 1mL in DMSO
$130.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's FLI-06 has been cited by 1 publications
  • Tan YJ, .et al. , Future Med Chem, 2018, Sep 1;10(17):2039-2057 PMID: 30066578
  • Biological Activity
    Discription FLI-06 is a Notch inhibitor and the early secretory pathway inhibitor. FLI-06 disrupts the Golgi apparatus in a manner distinct from that of brefeldin A and golgicide A.
    Targets
    Target Value
    Product Information
    Catalog Num A13815
    Formula C25H30N2O5
    Molecular Weight 438.52
    CAS Number 313967-18-9
    SMILES CC1=C(C(C2=C(N1)CC(CC2=O)(C)C)C3=CC=C(C=C3)[N+](=O)[O-])C(=O)OC4CCCCC4
    Synonyms FLI06,FLI 06
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 80 mg/mL (182.43 mM)
    Water Insoluble
    Ethanol 7 mg/mL (15.96 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.8 mL 114.02 mL 228.04 mL
    0.5 mM 4.56 mL 22.8 mL 45.61 mL
    1 mM 2.28 mL 11.4 mL 22.8 mL
    5 mM 0.46 mL 2.28 mL 4.56 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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