GS-9973 (Entospletinib)

Catalog No.: A13884
Syk inhibitor
GS-9973 is an oral inhibitor of spleen tyrosine kinase (Syk), with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
GS-9973 10mg
$100.00
In stock
GS-9973 25mg
$200.00
In stock
GS-9973 50mg
$260.00
In stock
GS-9973 100mg
$440.00
In stock
GS-9973 10mM * 1mL in DMSO
$75.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription GS-9973 is an oral inhibitor of spleen tyrosine kinase (Syk), with potential antineoplastic activity.
Targets
Target Value
Product Information
Catalog Num A13884
Formula C23H21N7O
Molecular Weight 411.46
CAS Number 1229208-44-9
SMILES C1COCCN1C2=CC=C(C=C2)NC3=NC(=CN4C3=NC=C4)C5=CC6=C(C=C5)C=NN6
Synonyms GS9973, GS 9973, Entospletinib
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 26 mg/mL (63.18 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+30% PEG 300+5% Tween 80+ddH2O 2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.3 mL 121.52 mL 243.04 mL
0.5 mM 4.86 mL 24.3 mL 48.61 mL
1 mM 2.43 mL 12.15 mL 24.3 mL
5 mM 0.49 mL 2.43 mL 4.86 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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