ICG-001

Catalog No.: A11039
Wnt/beta-catenin inhibitor
ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) .
Grouped product items
Product Name Price Stock Qty
ICG-001 5mg
$60.00
In stock
ICG-001 10mg
$100.00
In stock
ICG-001 25mg
$240.00
In stock
ICG-001 100mg
$550.00
In stock
ICG-001 10mM * 1mL in DMSO
$125.00
In stock
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Adooq Products cited in reputable paper
Adooq's ICG-001 has been cited by 5 publications
  • Seonmin Choi, .et al. , Yonsei Med J, 2021, Nov;62(11):1042-1051 PMID: 34672138
  • Jasper C.Munro, .et al. , Livest Sci, 2019, 229 (2019) 159-169
  • Kim JH, .et al. , Cell Rep, 2019, May 14;27(7):2105-2118.e5 PMID: 31091449
  • Yamaoka R, .et al. , J Surg Oncol, 2018, Sep;118(4):664-674 PMID: 30196535
  • Aida Y, .et al. , In Vitro Cell Dev Biol Anim, 2018, Jun;54(6):468-476 PMID: 29785536
  • Biological Activity
    Discription ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) .
    Targets
    Target Value
    Product Information
    Catalog Num A11039
    Formula C33H32N4O4
    Molecular Weight 548.6
    CAS Number 780757-88-2, 847591-62-2
    SMILES C1CN([C@H]2CN(C(=O)[C@@H](N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6
    Synonyms ICG001
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 99 mg/mL (180.45 mM)
    Water Insoluble
    Ethanol 10 mg/mL
    In vivo 2% DMSO+50% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.23 mL 91.14 mL 182.28 mL
    0.5 mM 3.65 mL 18.23 mL 36.46 mL
    1 mM 1.82 mL 9.11 mL 18.23 mL
    5 mM 0.36 mL 1.82 mL 3.65 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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