PRT-060318

Catalog No.: A15524
Syk inhibitor
PRT-060318 is a novel selective inhibitor of the tyrosine kinase Syk, as an approach to HIT treatment.
Grouped product items
Product Name Price Stock Qty
PRT-060318 5mg
$100.00
In stock
PRT-060318 10mg
$180.00
In stock
PRT-060318 25mg
$340.00
In stock
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Biological Activity
Discription PRT-060318 is a novel selective inhibitor of the tyrosine kinase Syk, as an approach to HIT treatment.
Product Information
Catalog Num A15524
Formula C18H24N6O
Molecular Weight 340.42
CAS Number 1194961-19-7
SMILES CC1=CC(=CC=C1)NC2=NC(=NC=C2C(=O)N)NC3CCCCC3N
Synonyms PRT 060318, PRT060318, PRT318, P142?C76.
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 66 mg/mL (159.67 mM)
Water 66 mg/mL (159.67 mM)
Ethanol Insoluble
In vivo water 71 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.38 mL 146.88 mL 293.75 mL
0.5 mM 5.88 mL 29.38 mL 58.75 mL
1 mM 2.94 mL 14.69 mL 29.38 mL
5 mM 0.59 mL 2.94 mL 5.88 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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