Cryptotanshinone
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Cryptotanshinone, a natural compound isolated from the roots of Salvia miltiorrhiza Bunge (Danshen), dramatically blocks STAT3 Tyr705 phosphorylation but not STAT3 Ser727 phosphorylation in DU145 cells, and significantly inhibits JAK2 phosphorylation with IC50 of ~5 μM without affecting the phosphorylation of upstream kinases c-Src and EGFR. | ||
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Catalog Num | A10244 |
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Formula | C19H20O3 |
Molecular Weight | 296.4 |
CAS Number | 35825-57-1 |
SMILES | C[C@H]1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C |
Synonyms | Tanshinone |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 5 mg/mL (16.87 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 1 mg/mL (3.37 mM) | ||
In vivo | 5% DMSO+40%PEG 300+5% Tween80 +ddH2O | 1.18 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 33.74 mL | 168.69 mL | 337.38 mL |
0.5 mM | 6.75 mL | 33.74 mL | 67.48 mL |
1 mM | 3.37 mL | 16.87 mL | 33.74 mL |
5 mM | 0.67 mL | 3.37 mL | 6.75 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2