Deferasirox

Catalog No.: A10293
Iron chelator
Deferasirox is a rationally-designed oral iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor.
Grouped product items
Product Name Price Stock Qty
Deferasirox 5mg
$45.00
In stock
Deferasirox 10mg
$65.00
In stock
Deferasirox 25mg
$80.00
In stock
Deferasirox 50mg
$125.00
In stock
Deferasirox 10mM * 1mL in DMSO
$96.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Deferasirox has been cited by 1 publications
  • Jamie L. Dombach, .et al. , PLoS Pathog, 2020, Dec; 16(12): e1009119 PMID: 33290418
  • Biological Activity
    Discription Deferasirox is a rationally-designed oral iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor.
    Product Information
    Catalog Num A10293
    Formula C21H15N3O4
    Molecular Weight 373.36
    CAS Number 201530-41-8
    SMILES C1=C/C(=C\2/N/C(=C\3/C=CC=CC3=O)/N(N2)C4=CC=C(C=C4)C(=O)O)/C(=O)C=C1
    Synonyms ICL-670, ICL-670A, CGP-72670
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 64 mg/mL (171.42 mM)
    Water Insoluble
    Ethanol 2 mg/mL
    In vivo 5% DMSO+40% PEG 300+5%Tween 80 +50 % H2O 3.5 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.78 mL 133.92 mL 267.84 mL
    0.5 mM 5.36 mL 26.78 mL 53.57 mL
    1 mM 2.68 mL 13.39 mL 26.78 mL
    5 mM 0.54 mL 2.68 mL 5.36 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    This equation is commonly abbreviated as: C1V1 = C2V2

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