Ki16425

Catalog No.: A10501
LPA Receptor Antagonist
Ki16425 is a LPA receptor antagonist with selectivity for LPA1 and LPA3 and exhibits Ki values of 0.34, 6.5, and 0.93 μM for the human LPA1, LPA2, and LPA3 receptors, respectively.
Grouped product items
Product Name Price Stock Qty
Ki16425 5mg
$50.00
In stock
Ki16425 10mg
$90.00
In stock
Ki16425 50mg
$360.00
In stock
Ki16425 100mg
$450.00
In stock
Ki16425 10mM * 1mL in DMSO
$107.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Ki16425 has been cited by 5 publications
  • Maria F Fernandes, .et al. , Int J Mol Sci, 2022, Apr 9;23(8):4163 PMID: 35456981
  • Rieko Suenaga, .et al. , PLoS One, 2022, Feb 3;17(2):e0263296 PMID: 35113924
  • Inoue A, .et al. , Cell, 2019, Jun 13;177(7):1933-1947 PMID: 31160049
  • Taniguchi R, .et al. , Nature, 2017, Aug 17;548(7667):356-360 PMID: 28792932
  • T. HASHIMOTO, .et al. , Br J Dermatol., 2015, Nov;173(5):1334-6 PMID: 26122943
  • Biological Activity
    Discription Ki16425 is a LPA receptor antagonist with selectivity for LPA1 and LPA3 and exhibits Ki values of 0.34, 6.5, and 0.93 μM for the human LPA1, LPA2, and LPA3 receptors, respectively.
    Product Information
    Catalog Num A10501
    Formula C23H23ClN2O5S
    Molecular Weight 475
    CAS Number 355025-24-0
    SMILES CC1=NOC(=C1NC(=O)OC(C)C2=CC=CC=C2Cl)C3=CC=C(C=C3)CSCCC(=O)O
    Synonyms Ki-16425
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 85 mg/mL (178.96 mM)
    Water Insoluble
    Ethanol 85 mg/mL (178.96 mM)
    In vivo 5% DMSO+95% Corn oil 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.05 mL 105.26 mL 210.53 mL
    0.5 mM 4.21 mL 21.05 mL 42.11 mL
    1 mM 2.11 mL 10.53 mL 21.05 mL
    5 mM 0.42 mL 2.11 mL 4.21 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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