MSX-122

Catalog No.: A12596
CXCR4 Inhibitor
MSX-122 is an orally bioavailable inhibitor of CXCR4 (IC50 = ~10 nM) with potential antineoplastic and antiviral activities. CXCR4 inhibitor MSX-122 binds to the chemokine receptor CXCR4, preventing the binding of stromal derived factor-1 (SDF-1) to the CXCR4 receptor and receptor activation, which may result in decreased tumor cell proliferation and migration.
Grouped product items
Product Name Price Stock Qty
MSX-122 10mg
$90.00
In stock
MSX-122 25mg
$180.00
In stock
MSX-122 50mg
$320.00
In stock
MSX-122 100mg
$550.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription MSX-122 is an orally bioavailable inhibitor of CXCR4 (IC50 = ~10 nM) with potential antineoplastic and antiviral activities. CXCR4 inhibitor MSX-122 binds to the chemokine receptor CXCR4, preventing the binding of stromal derived factor-1 (SDF-1) to the CXCR4 receptor and receptor activation, which may result in decreased tumor cell proliferation and migration.
Targets
Target Value
Product Information
Catalog Num A12596
Formula C16H16N6
Molecular Weight 292.34
CAS Number 897657-95-3
SMILES C1=CN=C(N=C1)NCC2=CC=C(C=C2)CNC3=NC=CC=N3
Synonyms MSX122, MSX 122
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 3 mg/mL (10.26 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.21 mL 171.03 mL 342.07 mL
0.5 mM 6.84 mL 34.21 mL 68.41 mL
1 mM 3.42 mL 17.1 mL 34.21 mL
5 mM 0.68 mL 3.42 mL 6.84 mL
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