Fludarabine (Fludara)

Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
Grouped product items
Product Name Price Stock Qty
Fludarabine 10mg
$40.00
In stock
Fludarabine 50mg
$130.00
In stock
Fludarabine 100mg
$230.00
In stock
Fludarabine (Fludara) 10mM * 1mL in DMSO
$70.00
In stock
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Adooq Products cited in reputable paper
Adooq's Fludarabine (Fludara) has been cited by 1 publications
  • Irene Dell'Anno, .et al. , Invest New Drugs, 2020, Dec 9 PMID: 33300108
  • Biological Activity
    Discription Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
    Targets
    Target Value
    Product Information
    Catalog Num A10396
    Formula C10H12FN5O4
    Molecular Weight 285.2
    CAS Number 21679-14-1
    SMILES C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)F)N
    Synonyms F-ara-A, NSC 118218
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 52 mg/mL (182.3 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 35.06 mL 175.32 mL 350.63 mL
    0.5 mM 7.01 mL 35.06 mL 70.13 mL
    1 mM 3.51 mL 17.53 mL 35.06 mL
    5 mM 0.7 mL 3.51 mL 7.01 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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