G007-LK

Catalog No.: A15528
TNKS inhibitor
G007-LK displays high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice,
Grouped product items
Product Name Price Stock Qty
G007-LK 5mg
$80.00
In stock
G007-LK 10mg
$140.00
In stock
G007-LK 25mg
$300.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's G007-LK has been cited by 1 publications
  • Dominic B. Bernkopf, .et al. , Nat Commun, 2019, 10:4251 PMID: 31534175
  • Biological Activity
    Discription G007-LK displays high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice,
    Targets
    Target Value
    Product Information
    Catalog Num A15528
    Formula C25H16ClN7O3S
    Molecular Weight 529.96
    CAS Number 1380672-07-0
    SMILES CS(=O)(=O)C1=CN=C(C=C1)C2=NN=C(N2C3=CC=CC=C3Cl)C=CC4=NN=C(O4)C5=CC=C(C=C5)C#N
    Synonyms G007 LK, G007LK
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 98 mg/mL (184.92 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.87 mL 94.35 mL 188.69 mL
    0.5 mM 3.77 mL 18.87 mL 37.74 mL
    1 mM 1.89 mL 9.43 mL 18.87 mL
    5 mM 0.38 mL 1.89 mL 3.77 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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