GSK J1

Catalog No.: A12918
Histone demethylase inhibitor
GSK J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX
Grouped product items
Product Name Price Stock Qty
GSK J1 10mg
$63.00
In stock
GSK J1 25mg
$126.00
In stock
GSK J1 50mg
$189.00
In stock
GSK J1 100mg
$315.00
In stock
Bulk Size
Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's GSK J1 has been cited by 2 publications
  • Nicolas A Fraunhoffer, .et al. , EBioMedicine, 2023, Jun;92:104602 PMID: 37148583
  • Guang Bai, .et al. , Epigenetics of Chronic Pain, 2019, Pages 1-48
  • Biological Activity
    Discription GSK J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX
    Targets
    Target Value
    Product Information
    Catalog Num A12918
    Formula C22H23N5O2
    Molecular Weight 389.45
    CAS Number 1373422-53-7
    SMILES C1CN(CCC2=CC=CC=C21)C3=CC(=NC(=N3)C4=CC=CC=N4)NCCC(=O)O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 70 mg/mL (179.74 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.68 mL 128.39 mL 256.77 mL
    0.5 mM 5.14 mL 25.68 mL 51.35 mL
    1 mM 2.57 mL 12.84 mL 25.68 mL
    5 mM 0.51 mL 2.57 mL 5.14 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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