KM 11060

Catalog No.: A15843
F508del-CFTR trafficking corrector
KM 11060 corrects F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane (~75%) and Inhibits PDE5 activity
Grouped product items
Product Name Price Stock Qty
KM 11060 10mg
$50.00
In stock
KM 11060 25mg
$100.00
In stock
KM 11060 50mg
$180.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription KM 11060 corrects F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane (~75%) and Inhibits PDE5 activity
Product Information
Catalog Num A15843
Formula C19H17Cl2N3O2S
Molecular Weight 422.33
CAS Number 774549-97-2
SMILES O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C(Cl)C=C4)=O
Synonyms KM-11060, KM11060
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 81 mg/mL (191.79 mM)
Water Insoluble
Ethanol 2 mg/mL (4.73 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.68 mL 118.39 mL 236.78 mL
0.5 mM 4.74 mL 23.68 mL 47.36 mL
1 mM 2.37 mL 11.84 mL 23.68 mL
5 mM 0.47 mL 2.37 mL 4.74 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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