R935788 (Fostamatinib disodium, R788)

Catalog No.: A10771
Syk Inhibitor
R935788 (Fostamatinib disodium) is a potent orally available inhibitor of Syk that inhibits tumor growth in the Eμ- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling.
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Product Name Price Stock Qty
R935788 5mg
$90.00
In stock
R935788 10mg
$130.00
In stock
R935788 50mg
$400.00
In stock
R935788 100mg
$638.00
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Biological Activity
Discription R935788 (Fostamatinib disodium) is a potent orally available inhibitor of Syk that inhibits tumor growth in the Eμ- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling.
Targets
Target Value
Product Information
Catalog Num A10771
Formula C23H24FN6O9P.2Na
Molecular Weight 624.4
CAS Number 1025687-58-4
SMILES CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.[Na+].[Na+]
Synonyms R-935788, Fostamatinib disodium, R788
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 5 mg/mL (8 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% CMC+0.25% Tween 80,pH6.5 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.02 mL 80.08 mL 160.15 mL
0.5 mM 3.2 mL 16.02 mL 32.03 mL
1 mM 1.6 mL 8.01 mL 16.02 mL
5 mM 0.32 mL 1.6 mL 3.2 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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This equation is commonly abbreviated as: C1V1 = C2V2

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