UMI-77
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family. | ||
---|---|---|---|
Targets |
|
Catalog Num | A14222 |
---|---|
Formula | C18H14BrNO5S2 |
Molecular Weight | 468.34 |
CAS Number | 518303-20-3 |
SMILES | C1=CC=C2C(=C1)C(=CC(=C2O)SCC(=O)O)NS(=O)(=O)C3=CC=C(C=C3)Br |
Synonyms | UMI 77,UMI77 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 92 mg/mL (196.43 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 92 mg/mL (196.43 mM) | ||
In vivo | 5% DMSO+30% PEG 300+dd H2O | 5 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.35 mL | 106.76 mL | 213.52 mL |
0.5 mM | 4.27 mL | 21.35 mL | 42.7 mL |
1 mM | 2.14 mL | 10.68 mL | 21.35 mL |
5 mM | 0.43 mL | 2.14 mL | 4.27 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2