VR23
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | VR23 is a small molecule that potently inhibited the activities of trypsin-like proteasomes (IC50 = 1 nM), chymotrypsin-like proteasomes (IC50 = 50-100 nM), and caspase-like proteasomes (IC50 = 3uM). | ||
---|---|---|---|
Targets |
|
Catalog Num | A13650 |
---|---|
Formula | C19H16ClN5O6S |
Molecular Weight | 477.88 |
CAS Number | 1624602-30-7 |
SMILES | ClC1=CC2=C(C(N3CCN(S(C4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)(=O)=O)CC3)=CC=N2)C=C1 |
Synonyms | VR-23, VR 23 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 29 mg/mL (60.68 mM) | |
Water | Warmed: 5 mg/mL (10.46 mM) | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.93 mL | 104.63 mL | 209.26 mL |
0.5 mM | 4.19 mL | 20.93 mL | 41.85 mL |
1 mM | 2.09 mL | 10.46 mL | 20.93 mL |
5 mM | 0.42 mL | 2.09 mL | 4.19 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2