Nepicastat (free base) (SYN-117)

Catalog No.: A10637
dopamine beta-hydroxylase inhibitor
Nepicastat is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.
Grouped product items
Product Name Price Stock Qty
Nepicastat 5mg
$150.00
In stock
Nepicastat 10mg
$270.00
In stock
Nepicastat 50mg
$718.00
In stock
Nepicastat 100mg
$1,300.00
In stock
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Biological Activity
Discription Nepicastat is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.
Product Information
Catalog Num A10637
Formula C14H15F2N3S
Molecular Weight 295.4
CAS Number 173997-05-2
SMILES C1CC2=C(C=C(C=C2C[C@H]1N3C(=CNC3=S)CN)F)F
Synonyms RS-25560-197
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 61 mg/mL (183.83 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.85 mL 169.26 mL 338.52 mL
0.5 mM 6.77 mL 33.85 mL 67.7 mL
1 mM 3.39 mL 16.93 mL 33.85 mL
5 mM 0.68 mL 3.39 mL 6.77 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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