JK 184

Catalog No.: A12925
Hedgehog inhibitor
JK184 is potent downstream hedgehog (Hh) signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM).
Grouped product items
Product Name Price Stock Qty
JK 184 10mg
$85.00
In stock
JK 184 25mg
$200.00
In stock
JK 184 50mg
$350.00
In stock
JK 184 100mg
$600.00
In stock
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Biological Activity
Discription JK184 is potent downstream hedgehog (Hh) signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM).
Product Information
Catalog Num A12925
Formula C19H18N4OS
Molecular Weight 350.44
CAS Number 315703-52-7
SMILES CCOC1=CC=C(C=C1)NC2=NC(=CS2)C3=C(N=C4N3C=CC=C4)C
Synonyms JK184
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 69 mg/mL (196.89 mM)
Water Insoluble
Ethanol 14 mg/mL (39.94 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.54 mL 142.68 mL 285.36 mL
0.5 mM 5.71 mL 28.54 mL 57.07 mL
1 mM 2.85 mL 14.27 mL 28.54 mL
5 mM 0.57 mL 2.85 mL 5.71 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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