Kobe0065

Catalog No.: A13135
Ras-Raf interaction inhibitor
Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells.
Grouped product items
Product Name Price Stock Qty
Kobe0065 10mg
$50.00
In stock
Kobe0065 25mg
$90.00
In stock
Kobe0065 50mg
$135.00
In stock
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Biological Activity
Discription Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells.
Targets
Target Value
Product Information
Catalog Num A13135
Formula C15H11ClF3N5O4S
Molecular Weight 449.79
CAS Number 436133-68-5
SMILES CC1=C(C=C(C=C1)NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])Cl
Synonyms Kobe-0065
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 85 mg/mL (188.98 mM)
Water Insoluble
Ethanol 12 mg/mL (26.68 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.23 mL 111.16 mL 222.33 mL
0.5 mM 4.45 mL 22.23 mL 44.47 mL
1 mM 2.22 mL 11.12 mL 22.23 mL
5 mM 0.44 mL 2.22 mL 4.45 mL
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