Lovastatin (Mevacor)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent). | ||
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Catalog Num | A11877 |
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Formula | C24H36O5 |
Molecular Weight | 404.54 |
CAS Number | 75330-75-5 |
SMILES | CC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 7 mg/mL (17.3 mM) | |
Water | Insoluble | ||
Ethanol | 5 mg/mL (12.36 mM) | ||
In vivo | 5% DMSO+40%PEG 300+ 5% Tween80 + 50% ddH2O | 2.3 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.72 mL | 123.6 mL | 247.19 mL |
0.5 mM | 4.94 mL | 24.72 mL | 49.44 mL |
1 mM | 2.47 mL | 12.36 mL | 24.72 mL |
5 mM | 0.49 mL | 2.47 mL | 4.94 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2