Ponesimod

Catalog No.: A13307
S1P1 receptor modulator
Ponesimod is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM.
Grouped product items
Product Name Price Stock Qty
Ponesimod 5mg
$100.00
In stock
Ponesimod 10mg
$170.00
In stock
Ponesimod 25mg
$360.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Ponesimod is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM.
Targets
Target Value
Product Information
Catalog Num A13307
Formula C23H25ClN2O4S
Molecular Weight 460.97
CAS Number 854107-55-4
SMILES O=C1N(C2=CC=CC=C2C)/C(S/C1=C\C3=CC=C(OC[C@H](O)CO)C(Cl)=C3)=N/CCC
Synonyms ACT-128800
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 82 mg/mL (177.88 mM)
Water Insoluble
Ethanol 82 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.69 mL 108.47 mL 216.93 mL
0.5 mM 4.34 mL 21.69 mL 43.39 mL
1 mM 2.17 mL 10.85 mL 21.69 mL
5 mM 0.43 mL 2.17 mL 4.34 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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