S-Ruxolitinib

Catalog No.: A14955
JAK inhibitor
S-Ruxolitinib is the chirality of INCB018424, is a potent and selective small-molecule Janus kinase 1 (JAK1) and JAK2 inhibitor.
Grouped product items
Product Name Price Stock Qty
S-Ruxolitinib 5mg
$60.00
In stock
S-Ruxolitinib 10mg
$80.00
In stock
S-Ruxolitinib 50mg
$120.00
In stock
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Biological Activity
Discription S-Ruxolitinib is the chirality of INCB018424, is a potent and selective small-molecule Janus kinase 1 (JAK1) and JAK2 inhibitor.
Targets
Target Value
Product Information
Catalog Num A14955
Formula C17H18N6
Molecular Weight 306.37
CAS Number 941685-37-6
SMILES C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
Synonyms INCB018424
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 59 mg/mL (192.57 mM)
Water 5 mg/mL (16.32 mM)
Ethanol 59 mg/mL (192.57 mM)
In vivo 0.5% CMC+0.25% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.64 mL 163.2 mL 326.4 mL
0.5 mM 6.53 mL 32.64 mL 65.28 mL
1 mM 3.26 mL 16.32 mL 32.64 mL
5 mM 0.65 mL 3.26 mL 6.53 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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