CHIR-124

Catalog No.: A11046
CHK Inhibitor
CHIR-124 is a novel and potent Chk1 inhibitor (IC50: 0.32 nM and 697 nM for Chk1 and Chk2 respectively).
Grouped product items
Product Name Price Stock Qty
CHIR-124 5mg
$70.00
In stock
CHIR-124 10mg
$120.00
In stock
CHIR-124 25mg
$220.00
In stock
CHIR-124 100mg
$620.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription CHIR-124 is a novel and potent Chk1 inhibitor (IC50: 0.32 nM and 697 nM for Chk1 and Chk2 respectively).
Targets
Target Value
Product Information
Catalog Num A11046
Formula C23H22ClN5O
Molecular Weight 419.9
CAS Number 405168-58-3
SMILES C1CN2CCC1[C@@H](C2)NC3=C4C=C(C=CC4=NC(=O)C3=C5NC6=CC=CC=C6N5)Cl
Synonyms CHIR124
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 6 mg/mL (14.29 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.82 mL 119.08 mL 238.15 mL
0.5 mM 4.76 mL 23.82 mL 47.63 mL
1 mM 2.38 mL 11.91 mL 23.82 mL
5 mM 0.48 mL 2.38 mL 4.76 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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