FIPI
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Isoforms of phospholipase D (PLD) cleave the head group from phospholipids, releasing the second messenger phosphatidic acid (PA), which can produce changes in Ras activation, cell spreading, stress fiber formation, chemotaxis, and membrane vesicle trafficking. FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM). |
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Catalog Num | A13895 |
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Formula | C23H24FN5O2 |
Molecular Weight | 421.5 |
CAS Number | 939055-18-2 |
SMILES | C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCNC(=O)C4=CC5=C(N4)C=CC(=C5)F |
Synonyms | 5-Fluoro-2-Indolyl des-Chlorohalopemide |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 40 mg/mL (94.9 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.72 mL | 118.62 mL | 237.25 mL |
0.5 mM | 4.74 mL | 23.72 mL | 47.45 mL |
1 mM | 2.37 mL | 11.86 mL | 23.72 mL |
5 mM | 0.47 mL | 2.37 mL | 4.74 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2