Nicergoline
α1A-adrenoceptor antagonist
Important Notice: For research use only. We do not sell to patients.
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α1A-adrenoceptor antagonist
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins. It has been found to increase mental agility and enhance clarity and perception. It decreases vascular resistance and increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. It has similar vasoactive properties in other areas of the body, particularly the lungs. Nicergoline is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy. |
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Catalog Num | A17422 |
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Formula | C24H26BrN3O3 |
Molecular Weight | 484.386 |
CAS Number | 27848-84-6 |
SMILES | O=C(C1=CC(Br)=CN=C1)OC[C@H](C[C@]23OC)CN(C)[C@]3([H])CC4=CN(C)C5=C4C2=CC=C5 |
Synonyms | Nicergoline, Nicotergoline, Nimergoline, Sermion |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 19 mg/mL (39.22 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.64 mL | 103.22 mL | 206.45 mL |
0.5 mM | 4.13 mL | 20.64 mL | 41.29 mL |
1 mM | 2.06 mL | 10.32 mL | 20.64 mL |
5 mM | 0.41 mL | 2.06 mL | 4.13 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2