Nimustine Hydrochloride

Catalog No.: A17583
Nimustine hydrochloride is an antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine.
Grouped product items
Product Name Price Stock Qty
Nimustine Hydrochloride 5mg
$45.00
In stock
Nimustine Hydrochloride 10mg
$70.00
In stock
Nimustine Hydrochloride 50mg
$220.00
In stock
Nimustine Hydrochloride 100mg
$400.00
In stock
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Biological Activity
Discription Nimustine hydrochloride is an antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine.
Product Information
Catalog Num A17583
Formula C9H14Cl2N6O2
Molecular Weight 309.15
CAS Number 55661-38-6
SMILES O=C(NCC1=CN=C(C)N=C1N)N(CCCl)N=O.[H]Cl
Synonyms CS 439 HCl; CS439 HCl; CS-439 HCl; CS-439; CS439; CS 439
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 60 mg/mL (194.08 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.35 mL 161.73 mL 323.47 mL
0.5 mM 6.47 mL 32.35 mL 64.69 mL
1 mM 3.23 mL 16.17 mL 32.35 mL
5 mM 0.65 mL 3.23 mL 6.47 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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