NSC 185058

Catalog No.: A17121
ATG4B antagonist
NSC 185058 is an inhibitor of ATG4B, a cysteine protease that activates LC3B during the initiation of autophagy.
Grouped product items
Product Name Price Stock Qty
NSC 185058 5mg
$160.00
In stock
NSC 185058 10mg
$280.00
In stock
NSC 185058 50mg
$980.00
In stock
NSC 185058 100mg
$1,680.00
In stock
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Biological Activity
Discription NSC 185058 is an inhibitor of ATG4B, a cysteine protease that activates LC3B during the initiation of autophagy.
Product Information
Catalog Num A17121
Formula C11H9N3S
Molecular Weight 215.3
CAS Number 39122-38-8
SMILES S=C(C1=NC=CC=C1)NC2=NC=CC=C2
Synonyms NSC185058, NSC-185058
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 43 mg/mL (199.74 mM)
Water Insoluble
Ethanol 21 mg/mL (97.55 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 46.45 mL 232.23 mL 464.47 mL
0.5 mM 9.29 mL 46.45 mL 92.89 mL
1 mM 4.64 mL 23.22 mL 46.45 mL
5 mM 0.93 mL 4.64 mL 9.29 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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