A-395

Catalog No.: A12999

PRC2 antagonist

A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM.
Grouped product items
Product Name Price Stock Qty
A-395 5mg
$90.00
In stock
A-395 10mg
$155.00
In stock
A-395 50mg
$460.00
In stock
A-395 100mg
$920.00
In stock
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Biological Activity
Discription A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM.
Product Information
Catalog Num A12999
Formula C26H35FN4O2S
Molecular Weight 486.65
CAS Number 2089148-72-9
SMILES O=S(N1CCN(C2=CC=C([C@H]3CN(C4C(C(F)=CC=C5)=C5CC4)C[C@@H]3N(C)C)C=C2)CC1)(C)=O
Synonyms A395, A 395
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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