Signaling Pathway
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| Discription | AMG-176 is a potent, selective and orally bioavailable MCL-1 inhibitor, with a Ki of 0.13 nM. | ||
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| Catalog Num | A18360 |
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| Formula | C33H41ClN2O5S |
| Molecular Weight | 613.21 |
| CAS Number | 1883727-34-1 |
| SMILES | CO[C@H]1\C=C\C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]6CC[C@@H]16)c3c2 |
| Synonyms | AMG-176; AMG 176; AMG176; tapotoclax; tapotoclaxum. |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
