Signaling Pathway
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| Discription | B-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively. | ||
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| Targets |
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| Catalog Num | A21834 |
|---|---|
| Formula | C26H21Cl3N8 |
| Molecular Weight | 551.86 |
| CAS Number | 1191385-19-9 |
| SMILES | CC1=CC=C2C(C=CN=C2NC3=CC=C(Cl)C=C3)=C1NC4=NC=CC=C4C5=NC=NC6=C5N=CN6.[H]Cl.[H]Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 96 mg/mL (173.95 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.12 mL | 90.6 mL | 181.21 mL |
| 0.5 mM | 3.62 mL | 18.12 mL | 36.24 mL |
| 1 mM | 1.81 mL | 9.06 mL | 18.12 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
