BAY 293

Catalog No.: A18319
SOS1 inhibitor
BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 21 nM.
Grouped product items
Product Name Price Stock Qty
BAY 293 5mg
$210.00
In stock
BAY 293 10mg
$400.00
In stock
BAY 293 50mg
$1,500.00
In stock
BAY 293 100mg
$2,800.00
In stock
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Biological Activity
Discription BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 21 nM.
Targets
Target Value
Product Information
Catalog Num A18319
Formula C25H28N4O2S
Molecular Weight 448.59
CAS Number 2244904-70-7
SMILES CNCC1=C(C=CC=C1)C1=CSC(=C1)[C@@H](C)NC1=NC(C)=NC2=C1C=C(OC)C(OC)=C2
Synonyms BAY293, BAY-293
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 88 mg/mL (196.17 mM)
Water Insoluble
Ethanol 88 mg/mL (196.17 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.29 mL 111.46 mL 222.92 mL
0.5 mM 4.46 mL 22.29 mL 44.58 mL
1 mM 2.23 mL 11.15 mL 22.29 mL
5 mM 0.45 mL 2.23 mL 4.46 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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