CB5083

Catalog No.: A15827
p97 inhibitor
CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models .
Grouped product items
Product Name Price Stock Qty
CB5083 5mg
$45.00
In stock
CB5083 10mg
$85.00
In stock
CB5083 25mg
$175.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models .
Targets
Target Value
Product Information
Catalog Num A15827
Formula C24H23N5O2
Molecular Weight 413.4
CAS Number 1542705-92-9
SMILES CC1=CC2=C(C=CC=C2N1C3=NC4=C(COCC4)C(=N3)NCC5=CC=CC=C5)C(=O)N
Synonyms CB-5083, CB 5083
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 74 mg/mL (178.97 mM)
Water Insoluble
Ethanol Warmed: 12 mg/mL (29.02 mM)
In vivo 0.5% CMC Na+5% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.19 mL 120.95 mL 241.9 mL
0.5 mM 4.84 mL 24.19 mL 48.38 mL
1 mM 2.42 mL 12.09 mL 24.19 mL
5 mM 0.48 mL 2.42 mL 4.84 mL
Useful Calculator

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