Dactolisib Tosylate

Catalog No.: A11327
dual PI3K and mTOR kinase inhibitor
Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.
Grouped product items
Product Name Price Stock Qty
Dactolisib Tosylate 50mg
$63.00
In stock
Dactolisib Tosylate 100mg
$109.00
In stock
Dactolisib Tosylate 500mg
$322.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.
Targets
Target Value
Product Information
Catalog Num A11327
Formula C37H31N5O4S
Molecular Weight 641.74
CAS Number 1028385-32-1
SMILES CN(C1=C2C3=CC(C4=CC5=CC=CC=C5N=C4)=CC=C3N=C1)C(N2C6=CC=C(C=C6)C(C)(C#N)C)=O.CC7=CC=C(S(=O)(O)=O)C=C7
Synonyms BEZ235 (Tosylate); NVP-BEZ 235 (Tosylate)
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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