Dolutegravir Sodium

Catalog No.: A16162
HIV integrase inhibitor
Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Grouped product items
Product Name Price Stock Qty
Dolutegravir Sodium 5mg
$70.00
In stock
Dolutegravir Sodium 10mg
$95.00
In stock
Dolutegravir Sodium 50mg
$399.00
In stock
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Biological Activity
Discription Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Targets
Target Value
Product Information
Catalog Num A16162
Formula C20H18F2N3NaO5
Molecular Weight 441.36
CAS Number 1051375-19-9
SMILES CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]
Synonyms DTG, GSK1349572
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 0.18 mg/mL (0.41 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.66 mL 113.29 mL 226.57 mL
0.5 mM 4.53 mL 22.66 mL 45.31 mL
1 mM 2.27 mL 11.33 mL 22.66 mL
5 mM 0.45 mL 2.27 mL 4.53 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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